Article

Distinct cell adhesion signature defines glioblastoma myeloid-derived suppressor cell subsets

2021-09-28

Abstract excerpt

Increased myeloid-derived suppressor cell (MDSC) frequency is associated with worse outcomes and poor therapeutic response in glioblastoma (GBM). Monocytic (m) MDSCs represent the predominant subset in the GBM microenvironment. However, the molecular basis of mMDSC enrichment in the tumor microenvironment compared to granulocytic (g) MDSCs has yet to be determined. Here, we report that mMDSCs and gMDSCs display di...

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Literature Corpus work: d25001a9-c09f-5ed8-85b4-86b75dac4610
DOI: 10.1101/2021.09.27.461995

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