Article
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes
15 Mar 2006
Abstract excerpt
Complex biological systems are best modeled as highly modular, fluid systems exhibiting a plasticity that allows them to adapt to a vast array of changing conditions. Here we highlight several novel network-based approaches to elucidate genetic networks underlying complex traits. These integrative genomic approaches combine large-scale genotypic and gene expression results in segregating mouse populations to...
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