Article

<i>Taf1</i> expression in mouse: novel transcripts and protein distribution

2025-09-12

Abstract excerpt

TATA-box binding protein associated factor 1 (TAF1) is the largest component of transcription factor IID (TFIID), a fundamental multiprotein complex for RNA polymerase II-mediated transcription. TAF1 is essential for promoter recognition, coactivator interaction, and normal development. Mutations in TAF1 cause developmental disorders and the lethal neurodegenerative disease X-linked dystonia-Parkinsonism (XDP). Ou...

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Literature Corpus work: a74f40b0-8899-5ba6-96d8-352c1f12c2ec
DOI: 10.1101/2025.09.08.674157

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