Article

Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells

2021-04-26

Abstract excerpt

<h4>SUMMARY</h4> The human definitive yolk sac is an important organ supporting the early developing embryo through nutrient supply and by facilitating the establishment of the embryonic circulatory system. However, the molecular and cellular biology of the human yolk sac remains largely obscure due to the lack of suitable in vitro models. Here, we show that human induced pluripotent stem cells (hiPSCs) co-cultu...

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Literature Corpus work: d2270777-ed67-5f4d-bf15-09654ea8a517
DOI: 10.1101/2021.04.25.441298

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Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cellsDOI 10.1101/2021.04.25.441298Read

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