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Generation of Bona Fide Fully Integrated Human Post-Implantation Structured Embryo Models (SEM) Derived Ex Utero Solely from Genetically Unmodified Naïve (HENSM) Pluripotent Stem Cells

2023-09-06

Abstract excerpt

<title>Abstract</title> <p>In this protocol we describe a detailed step-by-step protocol for the derivation of fully integrated human Stem-cell-derived Structured Embryo Models (SEMs) solely form transgene-free genetically unmodified naïve cells expanded in HENSM condition. This 8-day protocol opens the possibility of modeling the architectural organization of all known lineages and compartments of early post-imp...

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Literature Corpus work
5161e4b0-2811-5b24-86b3-af0d3735bacf
DOI
10.21203/rs.3.pex-2268/v1
Open publication

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Generation of Bona Fide Fully Integrated Human Post-Implantation Structured Embryo Models (SEM) Derived Ex Utero Solely from Genetically Unmodified Naïve (HENSM) Pluripotent Stem CellsDOI 10.21203/rs.3.pex-2268/v1
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