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hPSC-derived organoids: models of human development and disease

28 Aug 2020

Abstract excerpt

Organoids derived from human pluripotent stem cells (hPSCs) have emerged as important models for investigating human-specific aspects of development and disease. Here we discuss hPSC-derived organoids through the lens of development-highlighting how stages of human development align with the development of hPSC-derived organoids in the tissue culture dish. Using hPSC-derived lung and intestinal organoids as...

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PMID: 32857169
DOI: 10.1007/s00109-020-01969-w

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