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Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells

21 Mar 2018

Abstract excerpt

The rising interest in human induced pluripotent stem cell (hiPSC)-derived organoid culture has stemmed from the manipulation of various combinations of directed multi-lineage differentiation and morphogenetic processes that mimic organogenesis. Organoids are three-dimensional (3D) structures that are comprised of multiple cell types, self-organized to recapitulate embryonic and tissue development in vitro. This...

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PMID: 29561796
DOI: 10.3390/ijms19040936

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