Article

Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

2024-10-12

Abstract excerpt

<h4>SUMMARY</h4> The fetal liver is a hematopoietic organ, hosting a diverse and evolving progenitor population. While human liver organoids derived from pluripotent stem cells (PSCs) mimic aspects of embryonic and fetal development, they typically lack the complex hematopoietic niche and the interaction between hepatic and hematopoietic development. We describe the generation of human Fetal Liver-like Organoids...

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Literature Corpus work: 77756fb6-6bbb-51f9-abd1-122f95c24c6a
DOI: 10.1101/2024.10.11.617794

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