Article

Self-organized hemanoids derived from human iPSCs create a niche that produces definitive extraembryonic hematopoiesis

2026-05-08

Abstract excerpt

<h4>Summary</h4> Manufacturing red blood cells (RBCs) from human induced pluripotent stem cells (iPSCs) can improve our understanding of embryonic erythropoiesis, foster innovative treatments for RBC-related diseases, and ultimately address clinical blood supply shortages. However, existing systems face low efficiency, enucleation failure, and uncertainty about the develop-mental wave of cultured RBCs. We success...

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Literature Corpus work: e823173f-cce9-5ccf-a04f-ea3bc1338e75
DOI: 10.64898/2026.05.05.722134

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