Article

A UL26-PIAS1 complex antagonizes anti-viral gene expression during Human Cytomegalovirus infection

2024-02-19

Abstract excerpt

Viral disruption of innate immune signaling is a critical determinant of productive infection. The Human Cytomegalovirus (HCMV) UL26 protein prevents anti-viral gene expression during infection, yet the mechanisms involved are unclear. We used TurboID-driven proximity proteomics to identify putative UL26 interacting proteins during infection to address this issue. We find that UL26 forms a complex with several imm...

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Literature Corpus work: d1bf58ad-d104-5561-8b4a-0e8d84cd40d5
DOI: 10.1101/2024.02.19.580933

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