Article

Interferon-responsive genes are targeted during the establishment of human cytomegalovirus latency

2019-10-04

Abstract excerpt

Human cytomegalovirus (HCMV) latency is an active process which remodels the latently infected cell to optimise latent carriage and reactivation. This is achieved, in part, through the expression of viral genes, including the G-protein coupled receptor US28. Here, we use an unbiased proteomic screen to assess changes in host proteins induced by US28, revealing that interferon-inducible genes are downregulated by U...

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Literature Corpus work: de6c5e0f-1bf2-55ac-9844-a64659312914
DOI: 10.1101/791673

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