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Repetitive mild traumatic brain injury elicits a reactive microglial morphology and elevates serum neurofilament light levels, independent of NLRP3 inflammasome inhibition

2023-11-09

Abstract excerpt

There is growing evidence that a second mild traumatic brain injury (mTBI) sustained prior to cellular and neurological recovery from the first increases risk of cumulative pathological and neurological deficits. Despite this, the pathophysiology of single and repeated mTBI (rmTBI) is not well understood, and as such, no therapeutic interventions are available to mitigate the cumulative deficits induced. The Nod-l...

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Literature Corpus work
d17791db-b007-54f4-8b0f-69edffccac8a
DOI
10.21203/rs.3.rs-3566134/v1
Open publication

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Repetitive mild traumatic brain injury elicits a reactive microglial morphology and elevates serum neurofilament light levels, independent of NLRP3 inflammasome inhibitionDOI 10.21203/rs.3.rs-3566134/v1
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