Article

ASC contributes to sustained neuroinflammation and mild cognitive impairment after closed-head injury

2025-06-25

Abstract excerpt

Mild brain traumatic brain injury (mTBI) from closed-head injuries (CHI) can lead to prevalent neuropsychiatric disorders, including an increased risk for neurodegenerative diseases and dementia. Inflammasomes are molecular complexes crucial for neuroinflammation and secondary damage after trauma, however their role in mild CHI is poorly understood. In this study, we investigate the cellular expression of inflamma...

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Literature Corpus work: 1acef3ce-bcf6-5d9e-ad73-50fee03e96f5
DOI: 10.1101/2025.06.19.660521

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