Article

CD133 <sup>+</sup> progenitor cells promote pulmonary hypertension through CXCR4 signaling

2026-08-02

Abstract excerpt

<h4>Background</h4> Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling and smooth muscle cell accumulation, but the progenitor-like cells that contribute to this process remain incompletely defined. <h4>Methods</h4> We combined analyses of human pulmonary arterial hypertension lungs and experimental PH models with bulk and single-cell RNA sequencing, lineage tracing, inducible ablation...

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Literature Corpus work: d13fdb5a-fea1-5967-baf3-462b74607f51
DOI: 10.64898/2026.07.29.741640

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