Article

Emergence of disease-specific endothelial and stromal cell populations responsible for arterial remodeling during development of pulmonary arterial hypertension

2023-09-06

Abstract excerpt

<h4> Abstract </h4> Pulmonary arterial hypertension (PAH) is a severe and lethal pulmonary vascular disease characterized by arteriolar pruning and occlusive vascular remodeling leading to increased pulmonary vascular resistance and eventually right heart failure. While endothelial cell (EC) injury and apoptosis are known triggers for this disease, the mechanisms by which they lead to complex arterial remodeling...

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Literature Corpus work: a1a6a7b8-bdd4-5d59-b3c9-c0fcfed4adaa
DOI: 10.1101/2023.09.06.555321

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