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Cross-species analysis of experimental PH at single cell resolution reveals prominent contributions <i>Ednrb</i> <sup>+</sup> EC and <i>Dhcr24</i> <sup>+</sup> macrophage populations

2025-05-07

Abstract excerpt

<h4>Background</h4> Animal models are used widely to study pulmonary hypertension (PH). The cell populations that respond to disease-inducing stimuli in these models and their relationship to human disease remain incompletely defined. <h4>Materials and method</h4> This study analyzed the relationship between several rodent models of PH and human disease at single-cell resolution. scRNA-seq was performed on lungs...

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Literature Corpus work
8382cbc0-6c1b-52e2-bd86-7218ab50a46e
DOI
10.1101/2025.04.30.651587
Open publication

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Cross-species analysis of experimental PH at single cell resolution reveals prominent contributions <i>Ednrb</i> <sup>+</sup> EC and <i>Dhcr24</i> <sup>+</sup> macrophage populationsDOI 10.1101/2025.04.30.651587
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