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Charting the cellular landscape of pulmonary arterial hypertension through single-cell omics

3 May 2024

Abstract excerpt

This review examines how single-cell omics technologies, particularly single-cell RNA sequencing (scRNAseq), enhance our understanding of pulmonary arterial hypertension (PAH). PAH is a multifaceted disorder marked by pulmonary vascular remodeling, leading to high morbidity and mortality. The cellular pathobiology of this heterogeneous disease, involving various vascular and non-vascular cell types, is not fully...

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PMID: 38702687
DOI: 10.1186/s12931-024-02823-0

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