Article

A whole blood-based transcriptional risk score for nonobese type 2 diabetes predicts dynamic changes in glucose metabolic traits

2023-03-02

Abstract excerpt

<h4>Background</h4> The performance of peripheral blood transcriptional markers in evaluating the risk of type 2 diabetes (T2D) with normal weight is unknown. We developed a whole blood-based transcriptional risk score (wb-TRS) for nonobese T2D and assessed its contributions to disease risk and dynamic changes in glucose metabolism. <h4>Methods and findings</h4> We developed the wb-TRS in 1105 participants aged ≥4...

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Literature Corpus work: d132d187-af83-5369-9619-a9ce084e0004
DOI: 10.1101/2023.03.01.23286655

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