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Genetic Subtypes of Prediabetes, Healthy Lifestyle, and Risk of Type 2 Diabetes.

Diabetes - 1 Jul 2024

Li Yang, Chen Guo-Chong, Moon Jee-Young, Arthur Rhonda, Sotres-Alvarez Daniela, Daviglus Martha L, Pirzada Amber, Mattei Josiemer, Perreira Krista M, Rotter Jerome I, Taylor Kent D, Chen Yii-Der Ida, Wassertheil-Smoller Sylvia, Wang Tao, Rohan Thomas E, Kaufman Joel D, Kaplan Robert, Qi Qibin

Abstract excerpt

Prediabetes is a heterogenous metabolic state with various risks for development of type 2 diabetes (T2D). In this study, we used genetic data on 7,227 US Hispanic/Latino participants without diabetes from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and 400,149 non-Hispanic White participants without diabetes from the UK Biobank (UKBB) to calculate five partitioned polygenetic risk scores...

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Identifiers

PMID: 38602922
DOI: 10.2337/db23-0699
PMCID: PMC11189833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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