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Article

Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer Progression

2020-01-26

Abstract excerpt

<h4>SUMMARY</h4> Interleukin (IL)-11 is a member of the IL-6 family of cytokines and involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11 + ) cells are not fully understood. To characterize IL-11 + cells in vivo , we generated Il11 reporter mice. IL-11 + cells appeared in the colon of three murine tumor models, and a murine acute co...

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Literature Corpus work
d11d92d4-9efb-5da9-935c-2303c3e5dfe2
DOI
10.1101/2020.01.25.919795
Open publication

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Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer ProgressionDOI 10.1101/2020.01.25.919795
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