Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-11 Signaling as a Therapeutic Target for Cancer

1 Apr 2015

Abstract excerpt

IL-11 is a member of the IL-6 family of cytokines. While it was discovered over 20 years ago, we have very little understanding of the role of IL-11 during normal homeostasis and disease. Recently, IL-11 has gained interest for its newly recognized role in the pathogenesis of diseases that are attributed to deregulated mucosal homeostasis, including gastrointestinal cancers. IL-11 can increase the tumorigenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cytokine Signaling Pathways and Interactions
Share to Toxin Mechanisms and Immunotoxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25917632
DOI: 10.2217/imt.15.17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-11 Signaling as a Therapeutic Target for CancerPMID 25917632Read ↗

Exploring the role of interleukin 11 in cancer progression, patient survival, and therapeutic insightsSemantic proximity Read ↗

Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancerSemantic proximity Read ↗

More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancerSemantic proximity Read ↗

Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer ProgressionSemantic proximity Read ↗

Understanding interleukin 11 as a disease gene and therapeutic targetSemantic proximity Read ↗

Host IL11 Signaling Suppresses CD4+ T cell–Mediated Antitumor Responses to Colon Cancer in MiceSemantic proximity Read ↗

Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancerSemantic proximity Read ↗

Targeting IL-11 signaling in colon cancerSemantic proximity Read ↗

Inflammation and Cancer: A Temporal Perspective on Emerging Cellular and Molecular Mechanisms, Focusing on Gastrointestinal CancersSemantic proximity Read ↗

The Role of Interleukins in Colorectal Cancer.Semantic proximity Read ↗

IL-11RA is a Prognostic Biomarker and Correlated with Immune Infiltration in Lung AdenocarcinomaSemantic proximity Read ↗

IL-6 involvement in epithelial cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.