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Article

Understanding interleukin 11 as a disease gene and therapeutic target

6 Dec 2023

Abstract excerpt

Interleukin 11 (IL11) is an elusive member of the IL6 family of cytokines. While initially thought to be a haematopoietic and cytoprotective factor, more recent data show instead that IL11 is redundant for haematopoiesis and toxic. In this review, the reasons that led to the original misunderstandings of IL11 biology, which are now understandable, are explained with particular attention on the use of recombinant...

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Identifiers

PMID: 38054591
DOI: 10.1042/bcj20220160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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