Article

Esrrγa regulates nephron development and ciliogenesis by controlling prostaglandin synthesis and cooperation with Ppargc1a

2021-11-19

Abstract excerpt

Cilia are essential for the ontogeny and function of many tissues, including the kidney. In mammals, Esrrγ has been previously established as a significant determinant of renal health, with decreased expression linked to age related dysfunction, cyst formation, and kidney disease. Here, we report that the Esrrγ vertebrate ortholog estrogen related receptor gamma a ( esrrγa ) is essential for proper cell fate cho...

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Literature Corpus work: d0a4f3fb-eefb-5988-842f-73c298c8071c
DOI: 10.1101/2021.11.17.468871

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