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Article

Prostaglandin signaling regulates renal multiciliated cell specification and maturation

4 Apr 2019

Abstract excerpt

Significance Multiciliated cells (MCCs) have core roles in organ formation and function, where they control fluid flow and particle displacement. MCCs direct fluid movement in the brain and spinal cord, clearance of respiratory mucus, and ovum transport from the ovary to the uterus. Deficiencies in MCC functionality lead to hydrocephalus, chronic respiratory infections, and infertility. Prostaglandins are lipids...

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PMID: 30948642
DOI: 10.1073/pnas.1813492116

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