Article

Regulation of Indoleamine-3,5-dioxygenase 1 (IDO1) in Lung Epithelial Cells by Coronaviruses (SARS-CoV) and Cytokine Signaling

2021-09-07

Abstract excerpt

<title>Abstract</title> <p>Interferons (IFNs) and proinflammatory cytokines play an important role in the innate immune response to respiratory viruses, including coronaviruses (SARS-CoV). Metabolic profiling in the serum samples of coronavirus disease-19 (COVID-19) patients revealed altered cholesterol and tryptophan metabolism. Indoleamine-3,5-dioxygenase (IDO1) is the key enzyme involved in the tryptophan cata...

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Literature Corpus work: d0678fd5-b682-53b1-be92-9e0b00418d0e
DOI: 10.21203/rs.3.rs-871230/v1

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