Article

<i>De Novo</i> Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis

2020-03-24

Abstract excerpt

Phosphoinositides (PIPs) and their regulatory enzymes are key players in many cellular processes and are required for aspects of vertebrate development. Dysregulated PIP metabolism has been implicated in several human diseases, including a subset of skeletal myopathies that feature structural defects in the triad. The role of PIPs in skeletal muscle formation, and particularly triad biogenesis, has yet to be deter...

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Literature Corpus work: d0510149-195d-59e5-a5d4-b6ba27c710ec
DOI: 10.1101/2020.03.24.005306

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