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Article

Phosphatidylinositol-3,5-bisphosphate: metabolism and physiological functions.

Journal of biochemistry - 1 Sept 2013

Takasuga Shunsuke, Sasaki Takehiko

Abstract excerpt

Phosphatidylinositol (PtdIns) is a membrane phospholipid composed of diacylglycerol and a D-myo-inositol head group. In mammals, the hydroxyl groups at the D3, D4 and D5 positions of the inositol ring can be phosphorylated to yield seven phosphoinositide derivatives. PtdIns-3,5-bisphosphate [PtdIns(3,5)P2] is the most recently discovered species of phosphoinositide that is generated by the phosphorylation of...

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Identifiers

PMID: 23857703
DOI: 10.1093/jb/mvt064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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