Article

Early life lipid overload in Native American myopathy is phenocopied by stac3 knock out in zebrafish

2023-08-08

Abstract excerpt

Understanding the early stages of human congenital myopathies is critical for proposing strategies for improving skeletal muscle performance by restoring the functional integrity of cytoskeleton. SH3 and cysteine-rich domain 3 (Stac3) is a protein involved in nutrient sensing, and is an essential component of the excitation-contraction (EC) coupling machinery for Ca 2+ releasing. A mutation in STAC3 causes debilit...

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Literature Corpus work: cb3ae7bd-3695-56c6-957b-3a94c6d26b31
DOI: 10.21203/rs.3.rs-3225407/v1

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