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Article

The myotubularin family: novel phosphoinositide regulators.

IUBMB life - 1 Jan 2002

Nandurkar Harshal H, Huysmans Richard

Abstract excerpt

Phosphatidylinositol 3-phosphate [PtdIns(3)P] acts as a second messenger via the recruitment of diverse signalling proteins to various cellular compartments. Recent advances have highlighted the association of human diseases with mutations in phosphatases that regulate PtdIns(3)P levels. Myotubularin, the gene mutated in myotubular myopathy, functions as a lipid phosphatase with specificity for PtdIns(3)P. It is...

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Share to Multigene Family
Share to Myopathies, Structural, Congenital
Share to Phosphatidylinositols

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphorylation

Share to Protein Structure, Tertiary

Share to Protein Tyrosine Phosphatases

Share to Protein Tyrosine Phosphatases, Non-Receptor

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 12018406
DOI: 10.1080/15216540210812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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