Article

PI(4,5)P <sub>2</sub> role in Transverse-tubule membrane formation and muscle function

2024-01-31

Abstract excerpt

Transverse (T)-tubules – vast, tubulated domains of the muscle plasma membrane – are critical to maintain healthy skeletal and heart contractions. How the intricate T-tubule membranes are formed is not well understood, with challenges to systematically interrogate in muscle. We established the use of intact Drosophila larval body wall muscles as an ideal system to discover mechanisms that sculpt and maintain the T...

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Literature Corpus work: 8f9351cc-f541-5a30-a2f4-a94ea5cdd4ef
DOI: 10.1101/2024.01.31.578124

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