Article

CK2α/CSNK2A1 Induces Resistance to Doxorubicin Through SIRT6 Mediated Activation of the DNA Damage Repair Pathway

2021-06-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>CK2α/CSNK2A1 is involved in cancer progression by phosphorylating various signaling molecules. Considering the role of CSNK2A1 in cancer progression and phosphorylation of SIRT6 and the role of SIRT6 in chemoresistance through the DNA damage repair pathway, CSNK2A1 and SIRT6 might be involved in resistance to the conventional anti-cancer therapies.<bold>Methods</b...

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Literature Corpus work: d043059f-eab6-5681-b627-fe0d95dab6d1
DOI: 10.21203/rs.3.rs-624074/v1

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