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IL-1RA promotes oral squamous cell carcinoma malignancy through mitochondrial metabolism-mediated EGFR/JNK/SOX2 pathway

2023-06-02

Abstract excerpt

<title>Abstract</title> <p>Background Interleukin-1 receptor antagonist (IL-1RA), a member of the IL-1 family, has diverse roles in cancer development. However, the role of IL-1RA in oral squamous cell carcinoma (OSCC), in particular the underlying mechanisms, remains to be elucidated. Methods Tumor tissues from OSCC patients were assessed for protein expression by immunohistochemistry. Patient survival was eva...

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Literature Corpus work
6259d984-1b97-5195-992a-06be5dc93f1e
DOI
10.21203/rs.3.rs-2995954/v1
Open publication

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IL-1RA promotes oral squamous cell carcinoma malignancy through mitochondrial metabolism-mediated EGFR/JNK/SOX2 pathwayDOI 10.21203/rs.3.rs-2995954/v1
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