Article

Silencing Livin gene expression by RNA interference enhanced the chemotherapeutic sensitivity of drug-resistant MG-63 osteosarcoma cells to doxorubicin

2022-05-05

Abstract excerpt

<h4>Background: </h4> Osteosarcoma (OS) is a common malignant bone tumor of mesenchymal origin that mainly occurred in adolescent. Chemotherapy resistance is a major difficulty in the treatment of OS. The aim of the present study was to analyze the function of Livin in the drug resistance of osteosarcoma. <h4>Methods: </h4>: A drug-resistant MG-63 (MG-63/R) cell strain was established in vitro by continuously expo...

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Literature Corpus work: a1a7f353-30c6-5b9e-9196-af19737ff160
DOI: 10.21203/rs.3.rs-1618121/v1

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