Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caveolin‐1 promotes resistance to chemotherapy‐induced apoptosis in Ewing's sarcoma cells by modulating PKCα phosphorylation

17 Jul 2009

Abstract excerpt

Caveolin-1 (CAV1) has been implicated in the regulation of several signaling pathways and in oncogenesis. Previously, we identified CAV1 as a key determinant of the oncogenic phenotype and tumorigenic activity of cells from tumors of the Ewing's Sarcoma Family (ESFT). However, the possible CAV1 involvement in the chemotherapy resistance commonly presented by an ESFT subset has not been established to date. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Erythrocyte Function and Pathophysiology
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19609943
DOI: 10.1002/ijc.24754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caveolin‐1 promotes resistance to chemotherapy‐induced apoptosis in Ewing's sarcoma cells by modulating PKCα phosphorylationPMID 19609943Read ↗

Caveolin-1 ( CAV1 ) Is a Target of EWS/FLI-1 and a Key Determinant of the Oncogenic Phenotype and Tumorigenicity of Ewing's Sarcoma CellsSemantic proximity Read ↗

Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathwaySemantic proximity Read ↗

CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1–Dependent IGF-1 SignalingSemantic proximity Read ↗

Targeting PKIA/cAMP-EPAC signaling overcomes vincristine resistance in Ewing sarcomaSemantic proximity Read ↗

Targeting the EWSR1-FLI1 Oncogene-Induced Protein Kinase PKC-β Abolishes Ewing Sarcoma GrowthSemantic proximity Read ↗

Phosphocaveolin-1 Enforces Tumor Growth and Chemoresistance in RhabdomyosarcomaSemantic proximity Read ↗

Atypical protein kinase C zeta as a target for chemosensitization of tumor cells.Semantic proximity Read ↗

Protein kinase C-epsilon promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway.Semantic proximity Read ↗

CK2α/CSNK2A1 Induces Resistance to Doxorubicin Through SIRT6 Mediated Activation of the DNA Damage Repair PathwaySemantic proximity Read ↗

Nutlin-3a Is a Potential Therapeutic for Ewing SarcomaSemantic proximity Read ↗

Human leukemia K562 cell mutant (K562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C-epsilon, exhibits multidrug resistance phenotype, and expresses drug pump P-glycoprotein.Semantic proximity Read ↗

RNA inference-mediated caveolin-1 down-regulation decrease estrogen receptor alpha (ERα) signaling in human mammary epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.