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Article

An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes

2021-01-08

Abstract excerpt

Genetic manipulation of primary lymphocytes is crucial for both clinical purposes and fundamental research. Despite their broad use, we encountered a paucity of data on systematic comparison and optimization of retroviral vectors, the workhorses of genetic modification of primary lymphocytes. Here, we report the construction and validation of a versatile range of retroviral expression vectors. These vectors can be...

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Identifiers and source

Literature Corpus work
d0248e14-de9e-544f-a555-27e79c80864d
DOI
10.1101/2021.01.08.425881
Open publication

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An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytesDOI 10.1101/2021.01.08.425881
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