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Current Non-Viral-Based Strategies to Manufacture CAR-T Cells

21 Dec 2024

Abstract excerpt

The successful application of CAR-T cells in the treatment of hematologic malignancies has fundamentally changed cancer therapy. With increasing numbers of registered CAR-T cell clinical trials, efforts are being made to streamline and reduce the costs of CAR-T cell manufacturing while improving their safety. To date, all approved CAR-T cell products have relied on viral-based gene delivery and genomic...

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CAR-T cell therapy research
CRISPR and Genetic Engineering
Virus-based gene therapy research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39769449
DOI: 10.3390/ijms252413685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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