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Targeted gene delivery systems for T-cell engineering

16 May 2024

Abstract excerpt

T lymphocytes are indispensable for the host systems of defense against pathogens, tumors, and environmental threats. The therapeutic potential of harnessing the cytotoxic properties of T lymphocytes for antigen-specific cell elimination is both evident and efficacious. Genetically engineered T-cells, such as those employed in CAR-T and TCR-T cell therapies, have demonstrated significant clinical benefits in...

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PMID: 38753155
DOI: 10.1007/s13402-024-00954-6

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