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Evaluation of Precision of the <i>Plasmodium knowlesi</i> Growth Inhibition Assay for <i>Plasmodium vivax</i> Duffy-Binding Protein-based Malaria Vaccine Development

2024-01-24

Abstract excerpt

Recent data indicate increasing disease burden and importance of Plasmodium vivax ( Pv ) malaria. A robust assay will be essential for blood-stage Pv vaccine development. Results of the in vitro growth inhibition assay (GIA) with transgenic P. knowlesi ( Pk ) parasites expressing the Pv Duffy-binding protein region II ( Pv DBPII) correlate with in vivo protection in the first Pv DBPII controlled human ma...

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Literature Corpus work
d01aa716-d3e4-5505-a37e-b66b54996a12
DOI
10.1101/2024.01.23.576905
Open publication

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