Article

Rapid and iterative genome editing in the zoonotic malaria parasite <i>Plasmodium knowlesi</i> : New tools for <i>P. vivax</i> research

2019-03-28

Abstract excerpt

Tackling relapsing Plasmodium vivax and zoonotic Plasmodium knowlesi infections is critical to reducing malaria incidence and mortality worldwide. Understanding the biology of these important and related parasites was previously constrained by the lack of robust molecular and genetic approaches. Here, we establish CRISPR-Cas9 genome editing in a culture-adapted P. knowlesi strain and define parameters for optim...

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Literature Corpus work: 6b350fab-9dc5-58c6-842e-3ea5148cb2c3
DOI: 10.1101/590976

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