Article

The INO80 chromatin remodeling complex regulates histone H2A.Z mobility and the G1-S transition in oligodendrocyte precursors

2024-01-09

Abstract excerpt

<h4>SUMMARY</h4> Chromatin remodelling complexes (CRCs) participate in oligodendrocyte (OL) differentiation, survival and maintenance. We asked whether CRCs also control proliferation of OL precursors (OPs) – focusing on the INO80 complex, which is known to regulate proliferation of a variety of other cell types during development and disease. CRISPR/Cas9-mediated inactivation of Ino80 in vitro, or Cre-mediated...

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Literature Corpus work: d001183b-d456-5c7d-8cb2-14258e0c7ded
DOI: 10.1101/2024.01.09.574847

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