Article

KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma

2022-03-19

Abstract excerpt

<h4>Summary</h4> In solid tumors, G0-like states are likely critical for maintaining developmental hierarchies and cellular heterogeneity and promoting tumor growth/recurrence, yet little is known about tumor G0 states or regulation of their ingress/egress. To discover G0-like states and their regulators for glioblastoma (GBM), we analyzed G0 populations in an orthotopic model of GBM using single cell RNA-seq and...

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Literature Corpus work: 4084d0c4-a339-574f-9389-2a27c6bf24bd
DOI: 10.1101/2022.03.17.484768

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