Article

Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination

2022-09-16

Abstract excerpt

<h4>Summary</h4> Neurodevelopmental disorders are often characterized by abnormal production of myelin, an extension of the oligodendrocyte plasma membrane wrapped around axons to facilitate nerve conduction. However, the molecular mechanisms that control myelination during brain development are incompletely resolved. Here, we provide evidence that loss of ATRX, encoded by the gene mutated in the ATR-X intellectu...

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Literature Corpus work: f3fd47bf-4a36-5844-9ab5-83c35af11d0c
DOI: 10.1101/2022.09.15.508143

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