A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity

Abstract excerpt

<h4>ABSTRACT</h4> A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While the advent of single-cell transcriptomics has allowed for the discovery and identification of transcriptionally distinct cell populations present during lung development, the spatiotemporal dynamics...

Topics

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• Cell Lineage
• Congenital Diaphragmatic Hernia Studies
• Gene Expression Profiling
• Gene Expression Regulation, Developmental
• Lung
• Neonatal Respiratory Health Research
• Phenotype
• Transcriptome

Identifiers and source

Literature Corpus work

72c87d9f-aab2-54b3-a6ed-62229c9d266d

DOI

10.1101/2025.06.02.656433