Article

ER-positive breast cancer cells are poised for RET-mediated endocrine resistance

2017-01-06

Abstract excerpt

The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However, the expression of the RET receptor itself has not been directly linked to clinical cases of resistance, suggesting that additional factors are involved. We show that both ER+ endocrine resistant and sensitive breast cancers have functional RET tyrosine kinase signaling pathway, but that endoc...

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Literature Corpus work: cfe744f8-a929-560a-b0c9-822f688d15b2
DOI: 10.1101/098848

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