Article

Noradrenergic circuits in the forebrain control affective responses to novelty

2020-04-13

Abstract excerpt

<h4>Rationale</h4> In rodents, exposure to novel environments elicits initial anxiety-like behavior (neophobia) followed by intense exploration (neophilia) that gradually subsides as the environment becomes familiar. Thus, innate novelty-induced behaviors are useful indices of anxiety and motivation in animal models of psychiatric disease. Noradrenergic neurons are activated by novelty and implicated in explorato...

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Literature Corpus work: cfe539fe-4174-5475-91a9-d8f93dbaae7c
DOI: 10.1101/2020.04.11.037200

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