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Article

Differential stress-induced neuronal activation patterns in mouse lines selectively bred for high, normal or low anxiety.

PloS one - 1 Jan 2009

Muigg Patrik, Scheiber Sandra, Salchner Peter, Bunck Mirjam, Landgraf Rainer, Singewald Nicolas

Abstract excerpt

There is evidence for a disturbed perception and processing of emotional information in pathological anxiety. Using a rat model of trait anxiety generated by selective breeding, we previously revealed differences in challenge-induced neuronal activation in fear/anxiety-related brain areas between high (HAB) and low (LAB) anxiety rats. To confirm whether findings generalize to other species, we used the...

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Identifiers

PMID: 19399175
DOI: 10.1371/journal.pone.0005346
PMCID: PMC2670503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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