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Article

High novelty-seeking rats are resilient to negative physiological effects of the early life stress.

Stress (Amsterdam, Netherlands) - 1 Jan 2014

Clinton Sarah M, Watson Stanley J, Akil Huda

Abstract excerpt

Exposure to early life stress dramatically impacts adult behavior, physiology, and neuroendocrine function. Using rats bred for novelty-seeking differences and known to display divergent anxiety, depression, and stress vulnerability, we examined the interaction between early life adversity and genetic predisposition for high- versus low-emotional reactivity. Thus, bred Low Novelty Responder (bLR) rats, which...

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Source

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Identifiers

PMID: 24090131
DOI: 10.3109/10253890.2013.850670
PMCID: PMC4141530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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