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Article

Metabolic Endotoxemia Induces Sex-Specific Temporomandibular Joint Osteoarthritis via Leptin Signalling in Rats

2025-10-14

Abstract excerpt

<h4>Objective</h4> Temporomandibular joint (TMJ) osteoarthritis (OA) is a degenerative disease affecting the whole synovial joint, with a higher prevalence in women. While obesity is recognised as a risk factor for knee OA, its association with TMJ degeneration remains controversial. Recently, metabolic endotoxemia, characterised by a subclinical elevation of circulating lipopolysaccharide (LPS), has been propose...

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Literature Corpus work
cfd79b07-31b2-5633-92e7-f572cbe8e484
DOI
10.1101/2025.10.13.682179
Open publication

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Metabolic Endotoxemia Induces Sex-Specific Temporomandibular Joint Osteoarthritis via Leptin Signalling in RatsDOI 10.1101/2025.10.13.682179
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