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Article

Association Between Metabolically Different Adiposity Subtypes and Osteoarthritis: A Mendelian Randomization Study.

Arthritis care & research - 1 Apr 2023

Mulugeta Anwar, Eshetie Tesfahun C, Kassie Gizat M, Erku Daniel, Mekonnen Alemayehu, Lumsden Amanda, Hyppönen Elina

Abstract excerpt

OBJECTIVE: In this Mendelian randomization (MR) study, the objective was to investigate the causal effect of metabolically different adiposity subtypes on osteoarthritis. METHODS: We performed 2-sample MR using summary-level data for osteoarthritis (10,083 cases and 40,425 controls) from a genome-wide association using the UK Biobank, and for site-specific osteoarthritis from the Arthritis Research UK...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35313082
DOI: 10.1002/acr.24884
PMCID: PMC10952451

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