Article

Serglycin-Mediated Selective Reactivation of the Novel YAP/CRISPLD2 Developmental Axis Promotes Metastasis and Sorafenib Resistance in Hepatocellular Carcinoma

2020-12-29

Abstract excerpt

<h4>Background: </h4> The extracellular matrix (ECM) component serglycin promotes the epithelial-to-mesenchymal transition (EMT) and metastasis in an autocrine manner. However, the detailed mechanism underlying the roles of serglycin in Hepatocellular carcinoma (HCC) metastasis progression remains to be clarified. <h4>Methods: </h4> Analyzing 123 patients’ serum by ELISA to investigate the association between serg...

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Literature Corpus work: cf67d4cb-f710-563f-9a22-7907495f120a
DOI: 10.21203/rs.3.rs-135613/v1

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